Exportin 7 anticorps

N° du produit ABIN7232184

Cet anticorps anti-Exportin 7 est un anticorps Lapin Polyclonal détectant Exportin 7 dans WB et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour Exportin 7 anticorps (ABIN7232184)

Antigène: Exportin 7 (XPO7)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Exportin 7 anticorps

Fonction: XPO7 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of XPO7 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human XPO7 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Exportin 7

Antigène: Exportin 7 (XPO7)

Autre désignation: XPO7

Sujet: Rabbit Anti-XPO7 Polyclonal Antibody,Exportin-7, Exp7, Ran-binding protein 16,Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.,XPO7

Poids moléculaire: observerd band 119kDa

ID gène: 23039

UniProt: Q9UIA9