FANCA anticorps
Aperçu rapide pour FANCA anticorps (ABIN7220420)
Antigène
Voir toutes FANCA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- FANCA Polyclonal Antibody
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Specificité
- FANCA Polyclonal Antibody detects endogenous levels of FANCA protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human FANCA around the non-phosphorylation site of S1149
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FANCA (Fanconi Anemia Group A Protein (FANCA))
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Autre désignation
- FANCA
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Sujet
- Rabbit Anti-FANCA Polyclonal Antibody,FANCA, FAA, FACA, FANCH, Fanconi anemia group A protein, Protein FACA,The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.,Fanconi anemia group A protein
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ID gène
- 2175
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UniProt
- O15360
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Pathways
- Réparation de l'ADN
Antigène
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