Fibulin 5 anticorps (AA 140-220)

N° du produit ABIN7214900

L’anticorps anti-Fibulin 5 Polyclonal Lapin est utilisé pour la détection de Fibulin 5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour Fibulin 5 anticorps (AA 140-220) (ABIN7214900)

Antigène: Fibulin 5 (FBLN5)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibulin 5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Fibulin 5 anticorps

Épitope: AA 140-220

Fonction: Rabbit Anti-Fibulin-5 Polyclonal Antibody

Specificité: Fibulin-5 Polyclonal Antibody detects endogenous levels of Fibulin-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Fibulin-5 at AA range: 140-220

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Fibulin 5

Antigène: Fibulin 5 (FBLN5)

Autre désignation: Fibulin-5

Sujet: FBLN5, DANCE, Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50Fibulin-5 encoded by FBLN5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Poids moléculaire: 50kD

ID gène: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome