FKBP5 anticorps
Aperçu rapide pour FKBP5 anticorps (ABIN7228544)
Antigène
Voir toutes FKBP5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-FKBP5 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of FKBP5 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human FKBP5 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- FKBP5 (FK506 Binding Protein 5 (FKBP5))
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Autre désignation
- FKBP5
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Sujet
- 51 kDa FK506-binding protein, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin, RotamaseThe protein encoded by FKBP5 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. FKBP5 has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 50kD
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ID gène
- 2289
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UniProt
- Q13451
Antigène
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