GPBAR1 anticorps (AA 30-110)

N° du produit ABIN7219850

L’anticorps Lapin Polyclonal anti-GPBAR1 a été validé pour ELISA et IF. Il convient pour détecter GPBAR1 dans des échantillons de Humain.

Aperçu rapide pour GPBAR1 anticorps (AA 30-110) (ABIN7219850)

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPBAR1 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Détail du produit anti-GPBAR1 anticorps

Épitope: AA 30-110

Fonction: TGR5 Polyclonal Antibody

Specificité: TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human TGR5 at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur GPBAR1

Antigène: GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))

Autre désignation: TGR5

Sujet: Rabbit Anti-TGR5 Polyclonal Antibody,GPBAR1, TGR5, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, hGPCR19, Membrane-type receptor for bile acids, M-BAR, hBG37, BG37,GPBAR1 encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.,G-protein coupled bile acid receptor 1

ID gène: 151306

UniProt: Q8TDU6

Pathways: Signalisation WNT, Hormone Transport, Sensory Perception of Sound