GPSM2 anticorps
Aperçu rapide pour GPSM2 anticorps (ABIN7228762)
Antigène
Voir toutes GPSM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-GPSM2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of GPSM2 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human GPSM2 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
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Autre désignation
- GPSM2
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Sujet
- G-protein-signaling modulator 2, Mosaic protein LGNThe protein encoded by GPSM2 belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. GPSM2 (G Protein Signaling Modulator 2) is a Protein Coding gene. Diseases associated with GPSM2 include Chudley-Mccullough Syndrome and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb.
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Poids moléculaire
- 75kD
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ID gène
- 29899
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UniProt
- P81274
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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