GABBR2 anticorps

N° du produit ABIN7226024

Cet anticorps Lapin Polyclonal détecte spécifiquement GABBR2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour GABBR2 anticorps (ABIN7226024)

Antigène: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABBR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GABBR2 anticorps

Fonction: Rabbit Anti-GABAB R2 Polyclonal Antibody

Specificité: GABAB R2 Polyclonal Antibody detects endogenous levels of GABAB R2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human GABAB R2 around the non-phosphorylation site of S893

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GABBR2

Antigène: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Autre désignation: GABAB R2

Sujet: GABBR2, GPR51, GPRC3B, Gamma-aminobutyric acid type B receptor subunit 2, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51, HG20The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of GABBR2 (gamma-aminobutyric acid type B receptor subunit 2) have been associated with nicotine dependence.

Poids moléculaire: 105kD

ID gène: 9568

UniProt: O75899

Pathways: cAMP Metabolic Process