GJB2 anticorps (Internal Region)

N° du produit ABIN7214294

Cet anticorps anti-GJB2 Polyclonal Lapin (ABIN7214294) détecte spécifiquement GJB2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GJB2 anticorps (Internal Region) (ABIN7214294)

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GJB2 anticorps

Épitope: Internal Region

Fonction: Connexin-26 Polyclonal Antibody

Specificité: Connexin-26 Polyclonal Antibody detects endogenous levels of Connexin-26 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Connexin-26

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur GJB2

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Autre désignation: Connexin-26

Sujet: Rabbit Anti-Connexin-26 Polyclonal Antibody,GJB2, Gap junction beta-2 protein, Connexin-26, Cx26,GJB2 encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in GJB2 are responsible for as much as 50 % of pre-lingual, recessive deafness.,Gap junction beta-2 protein

Poids moléculaire: observerd band 26kDa

ID gène: 2706

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization