Gelsolin anticorps

N° du produit ABIN7228646

L’anticorps Lapin Polyclonal anti-Gelsolin a été validé pour WB et ELISA. Il convient pour détecter Gelsolin dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Gelsolin anticorps (ABIN7228646)

Antigène: Gelsolin (GSN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Gelsolin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Gelsolin anticorps

Fonction: GELS Polyclonal Antibody

Specificité: The antibody detects endogenous levels of GELS protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human GELS protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Gelsolin

Antigène: Gelsolin (GSN)

Autre désignation: GELS

Sujet: Rabbit Anti-GELS Polyclonal Antibody,Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin,Gelsolin encoded by GSN binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for GSN. GSN (Gelsolin) is a Protein Coding gene. Diseases associated with GSN include Amyloidosis, Finnish Type and Lattice Corneal Dystrophy Type Ii. Among its related pathways are Apoptosis and survival Caspase cascade and N-cadherin signaling events.,GELS

Poids moléculaire: observerd band 86kDa

ID gène: 2934

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy