HRG anticorps

N° du produit ABIN7228966

L’anticorps anti-HRG Polyclonal Lapin est utilisé pour la détection de HRG dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour HRG anticorps (ABIN7228966)

Antigène: HRG (Histidine-Rich Glycoprotein (HRG))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRG est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HRG anticorps

Fonction: Rabbit Anti-HRG Polyclonal Antibody

Specificité: The antibody detects endogenous levels of HRG protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human HRG protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HRG

Antigène: HRG (Histidine-Rich Glycoprotein (HRG))

Autre désignation: HRG

Sujet: Histidine-rich glycoprotein, Histidine-proline-rich glycoprotein, HPRGThis histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. Histidine Rich Glycoprotein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Poids moléculaire: 57kD

ID gène: 3273

UniProt: P04196