HDAC4 anticorps
Aperçu rapide pour HDAC4 anticorps (ABIN7215208)
Antigène
Voir toutes HDAC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- HDAC4 Polyclonal Antibody
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Specificité
- HDAC4 Polyclonal Antibody detects endogenous levels of HDAC4 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human HDAC4 around the non-phosphorylation site of S632
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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Autre désignation
- HDAC4
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Sujet
- Rabbit Anti-HDAC4 Polyclonal Antibody,HDAC4, KIAA0288, Histone deacetylase 4, HD4,Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. Histone deacetylase 4 does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.,Histone deacetylase 4
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Poids moléculaire
- observerd band 119kDa
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ID gène
- 9759
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UniProt
- P56524
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Antigène
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