HLA-E anticorps

N° du produit ABIN7228932

L’anticorps anti-HLA-E Polyclonal Lapin est utilisé pour la détection de HLA-E dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour HLA-E anticorps (ABIN7228932)

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-E est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HLA-E anticorps

Fonction: Rabbit Anti-HLAE Polyclonal Antibody

Specificité: The antibody detects endogenous levels of HLAE protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human HLAE protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HLA-E

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Autre désignation: HLAE

Sujet: HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen EHLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Poids moléculaire: 39kD

ID gène: 3133

UniProt: P13747

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response