HAP1 anticorps

N° du produit ABIN7228840

L’anticorps anti-HAP1 Polyclonal Lapin est utilisé pour la détection de HAP1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour HAP1 anticorps (ABIN7228840)

Antigène: HAP1 (Huntingtin Associated Protein 1 (HAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HAP1 anticorps

Fonction: Rabbit Anti-HAP1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of HAP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human HAP1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HAP1

Antigène: HAP1 (Huntingtin Associated Protein 1 (HAP1))

Autre désignation: HAP1

Sujet: Huntingtin-associated protein 1, HAP-1, Neuroan 1HAP1 (Huntingtin Associated Protein 1) is a Protein Coding gene. Diseases associated with HAP1 include Huntington Disease and Spinocerebellar Ataxia 17. Among its related pathways are GABAergic synapse and fMLP Pathway. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. HAP1 encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport.

Poids moléculaire: 73kD

ID gène: 9001

UniProt: P54257

Pathways: Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus