IDO1 anticorps

N° du produit ABIN7228998

L’anticorps Lapin Polyclonal anti-IDO1 a été validé pour WB et ELISA. Il convient pour détecter IDO1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IDO1 anticorps (ABIN7228998)

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDO1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IDO1 anticorps

Fonction: I23O1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of I23O1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human I23O1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur IDO1

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Autre désignation: I23O1

Sujet: Rabbit Anti-I23O1 Polyclonal Antibody,Indoleamine 2,3-dioxygenase 1, IDO-1, Indoleamine-pyrrole 2,3-dioxygenase,IDO1 encodes indoleamine 2,3-dioxygenase (IDO--a heme enzyme) that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.,I23O1

Poids moléculaire: observerd band 44kDa

ID gène: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation