IRF3 anticorps (pSer385)

N° du produit ABIN7221858

L’anticorps Lapin Polyclonal anti-IRF3 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter IRF3 dans des échantillons de Humain.

Aperçu rapide pour IRF3 anticorps (pSer385) (ABIN7221858)

Antigène: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IRF3 anticorps

Épitope: pSer385

Fonction: IRF-3 (phospho Ser385) Polyclonal Antibody

Specificité: Phospho-IRF-3 (S385) Polyclonal Antibody detects endogenous levels of IRF-3 protein only when phosphorylated at S385.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human IRF-3 Phospho-Ser385

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur IRF3

Antigène: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Autre désignation: IRF-3

Sujet: Rabbit Anti-IRF-3 (phospho Ser385) Polyclonal Antibody,IRF3, Interferon regulatory factor 3, IRF-3,IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,Interferon regulatory factor 3

Poids moléculaire: observerd band 57kDa

ID gène: 3661

UniProt: Q14653

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades