IL9 Receptor anticorps (pSer519)

N° du produit ABIN7221790

L’anticorps anti-IL9 Receptor Polyclonal Lapin est utilisé pour la détection de IL9 Receptor dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour IL9 Receptor anticorps (pSer519) (ABIN7221790)

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL9 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IL9 Receptor anticorps

Épitope: pSer519

Fonction: Rabbit Anti-IL-9R (phospho Ser519) Polyclonal Antibody

Specificité: Phospho-IL-9R (S519) Polyclonal Antibody detects endogenous levels of IL-9R protein only when phosphorylated at S519.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human IL-9R Phospho-Ser519

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IL9 Receptor

Antigène: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Autre désignation: IL-9R

Sujet: IL9R, Interleukin-9 receptor, IL-9 receptor, IL-9R, CD antigen CD129The protein encoded by IL9R is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 57kD

ID gène: 3581

UniProt: Q01113

Pathways: Signalistation JAK/STAT, Growth Factor Binding