IRAK3 anticorps (AA 460-540)

N° du produit ABIN7219272

L’anticorps anti-IRAK3 Polyclonal Lapin est utilisé pour la détection de IRAK3 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour IRAK3 anticorps (AA 460-540) (ABIN7219272)

Antigène: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IRAK3 anticorps

Épitope: AA 460-540

Fonction: Rabbit Anti-IRAK-M Polyclonal Antibody

Specificité: IRAK-M Polyclonal Antibody detects endogenous levels of IRAK-M protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human IRAK-M at AA range: 460-540

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IRAK3

Antigène: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Autre désignation: IRAK-M

Sujet: IRAK3, Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-MIRAK3 encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. Interleukin-1 receptor-associated kinase 3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 68kD

ID gène: 11213

UniProt: Q9Y616

Pathways: Signalisation TLR, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades