KDM5B anticorps

N° du produit ABIN7229274

Cet anticorps anti-KDM5B est un anticorps Lapin Polyclonal détectant KDM5B dans WB et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour KDM5B anticorps (ABIN7229274)

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM5B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-KDM5B anticorps

Fonction: KDM5B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of KDM5B protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human KDM5B protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur KDM5B

Antigène: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Autre désignation: KDM5B

Sujet: Rabbit Anti-KDM5B Polyclonal Antibody,Lysine-specific demethylase 5B, Cancer/testis antigen 31, CT31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1,KDM5B encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. KDM5B (Lysine Demethylase 5B) is a Protein Coding gene. Diseases associated with KDM5B include Ascending Colon Cancer and Autosomal Dominant Non-Syndromic Intellectual Disability. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.,KDM5B

Poids moléculaire: observerd band 169kDa

ID gène: 10765

UniProt: Q9UGL1

Pathways: L'effet Warburg