MASP2 anticorps (AA 200-280)

N° du produit ABIN7219136

Cet anticorps anti-MASP2 Polyclonal Lapin (ABIN7219136) détecte spécifiquement MASP2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MASP2 anticorps (AA 200-280) (ABIN7219136)

Antigène: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MASP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MASP2 anticorps

Épitope: AA 200-280

Fonction: Rabbit Anti-MASP-2 Polyclonal Antibody

Specificité: MASP-2 Polyclonal Antibody detects endogenous levels of MASP-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human MASP-2 at AA range: 200-280

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MASP2

Antigène: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Autre désignation: MASP-2

Sujet: MASP2, Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2MASP2 encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Poids moléculaire: 75kD

ID gène: 10747

UniProt: O00187

Pathways: Système du Complément