MRGPRD anticorps

N° du produit ABIN7229754

Cet anticorps anti-MRGPRD Polyclonal Lapin (ABIN7229754) détecte spécifiquement MRGPRD dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MRGPRD anticorps (ABIN7229754)

Antigène: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRGPRD est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MRGPRD anticorps

Fonction: Rabbit Anti-MRGRD Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MRGRD protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MRGRD protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MRGPRD

Antigène: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Autre désignation: MRGRD

Sujet: Mas-related G-protein coupled receptor member D, Beta-alanine receptor, G-protein coupled receptor TGR7MRGPRD (MAS Related GPR Family Member D) is a Protein Coding gene. Among its related pathways are ACE Inhibitor Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

Poids moléculaire: 35kD

ID gène: 116512

UniProt: Q8TDS7