MMP7 anticorps (AA 190-270)

N° du produit ABIN7215686

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP7 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Rat, Souris et Singe.

Aperçu rapide pour MMP7 anticorps (AA 190-270) (ABIN7215686)

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-MMP7 anticorps

Épitope: AA 190-270

Fonction: Rabbit Anti-MMP-7 Polyclonal Antibody

Specificité: MMP-7 Polyclonal Antibody detects endogenous levels of MMP-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human MMP-7 at AA range: 190-270

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MMP7

Antigène: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Autre désignation: MMP-7

Sujet: MMP7, MPSL1, PUMP1, Matrilysin, Matrin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, Uterine metalloproteinaseMMP7 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Matrilysin is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.

Poids moléculaire: 29kD

ID gène: 4316

UniProt: P09237

Pathways: Production of Molecular Mediator of Immune Response