MXI1 anticorps

N° du produit ABIN7229804

L’anticorps Lapin Polyclonal anti-MXI1 a été validé pour WB et ELISA. Il convient pour détecter MXI1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MXI1 anticorps (ABIN7229804)

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MXI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MXI1 anticorps

Fonction: MXI1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MXI1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human MXI1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MXI1

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Autre désignation: MXI1

Sujet: Rabbit Anti-MXI1 Polyclonal Antibody,Max-interacting protein 1, Max interactor 1, Class C basic helix-loop-helix protein 11, bHLHc11,Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. MAX Interactor 1, Dimerization Protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1

Poids moléculaire: observerd band 25kDa

ID gène: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location