Manic Fringe anticorps (AA 30-110)

N° du produit ABIN7222460

L’anticorps Lapin Polyclonal anti-Manic Fringe a été validé pour WB et ELISA. Il convient pour détecter Manic Fringe dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Manic Fringe anticorps (AA 30-110) (ABIN7222460)

Antigène: Manic Fringe (MFNG) (MFNG)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Manic Fringe est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Manic Fringe anticorps

Épitope: AA 30-110

Fonction: Manic Fringe Polyclonal Antibody

Specificité: Manic Fringe Polyclonal Antibody detects endogenous levels of Manic Fringe protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Manic Fringe at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Manic Fringe

Antigène: Manic Fringe (MFNG) (MFNG)

Autre désignation: Manic Fringe

Sujet: Rabbit Anti-Manic Fringe Polyclonal Antibody,MFNG, Beta-1, 3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,MFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.,Beta-1,3-N-acetylglucosaminyltransferase manic fringe

Poids moléculaire: observerd band 38kDa

ID gène: 4242

UniProt: O00587

Pathways: Signalisation Notch