MUC4 anticorps (AA 1970-2050)

N° du produit ABIN7229790

Cet anticorps Lapin Polyclonal détecte spécifiquement MUC4 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MUC4 anticorps (AA 1970-2050) (ABIN7229790)

Antigène: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MUC4 anticorps

Épitope: AA 1970-2050

Fonction: Rabbit Anti-MUC4 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MUC4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MUC4 protein at AA range: 1970-2050

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MUC4

Antigène: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Autre désignation: MUC4

Sujet: Mucin-4, MUC-4, Ascites sialoglycoprotein, ASGP, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucinMUC4 (Mucin 4, Cell Surface Associated) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and HIV Life Cycle. The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. MUC4 encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of MUC4 have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. MUC4 contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.

Poids moléculaire: 238kD

ID gène: 4585

UniProt: Q99102

Pathways: Regulation of Leukocyte Mediated Immunity