Menin anticorps (AA 150-230)

N° du produit ABIN7215738

Cet anticorps Lapin Polyclonal détecte spécifiquement Menin dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Menin anticorps (AA 150-230) (ABIN7215738)

Antigène: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Menin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Menin anticorps

Épitope: AA 150-230

Fonction: Menin Polyclonal Antibody

Specificité: Menin Polyclonal Antibody detects endogenous levels of Menin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Menin at AA range: 150-230

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Menin

Antigène: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Autre désignation: Menin

Sujet: Rabbit Anti-Menin Polyclonal Antibody,MEN1, SCG2, Menin,MEN1 encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.,Menin

Poids moléculaire: observerd band 67kDa

ID gène: 4221

UniProt: O00255

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity