MSH3 anticorps (AA 30-110)

N° du produit ABIN7215890

L’anticorps Lapin Polyclonal anti-MSH3 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter MSH3 dans des échantillons de Humain.

Aperçu rapide pour MSH3 anticorps (AA 30-110) (ABIN7215890)

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSH3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MSH3 anticorps

Épitope: AA 30-110

Fonction: MSH3 Polyclonal Antibody

Specificité: MSH3 Polyclonal Antibody detects endogenous levels of MSH3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human MSH3 at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MSH3

Antigène: MSH3 (MutS Homolog 3 (MSH3))

Autre désignation: MSH3

Sujet: Rabbit Anti-MSH3 Polyclonal Antibody,MSH3, DUC1, DUG, DNA mismatch repair protein Msh3, hMSH3, Divergent upstream protein, DUP, Mismatch repair protein 1, MRP1,DNA mismatch repair protein Msh3 encoded by MSH3 forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.,DNA mismatch repair protein Msh3

Poids moléculaire: observerd band 127kDa

ID gène: 4437

UniProt: P20585

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response