MAX anticorps (pSer2)

N° du produit ABIN7222374

L’anticorps anti-MAX Polyclonal Lapin est utilisé pour la détection de MAX dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, IHC et IF.

Aperçu rapide pour MAX anticorps (pSer2) (ABIN7222374)

Antigène: MAX (MYC Associated Factor X (MAX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAX est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MAX anticorps

Épitope: pSer2

Fonction: Rabbit Anti-Max (phospho Ser2) Polyclonal Antibody

Specificité: Phospho-Max (S2) Polyclonal Antibody detects endogenous levels of Max protein only when phosphorylated at S2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human Max Phospho-Ser2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MAX

Antigène: MAX (MYC Associated Factor X (MAX))

Autre désignation: Max

Sujet: MAX, BHLHD4, Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor XThe protein encoded by MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

ID gène: 4149

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases