MNDA anticorps (AA 350-430)
Aperçu rapide pour MNDA anticorps (AA 350-430) (ABIN7222516)
Antigène
Voir toutes MNDA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 350-430
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Fonction
- MNDA Polyclonal Antibody
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Specificité
- MNDA Polyclonal Antibody detects endogenous levels of MNDA protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the C-terminal region of human MNDA at AA range: 350-430
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
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Autre désignation
- MNDA
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Sujet
- Rabbit Anti-MNDA Polyclonal Antibody,MNDA, Myeloid cell nuclear differentiation antigen,The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.,Myeloid cell nuclear differentiation antigen
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Poids moléculaire
- observerd band 46kDa
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ID gène
- 4332
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UniProt
- P41218
Antigène
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