MNDA anticorps (AA 350-430)

N° du produit ABIN7222516

L’anticorps anti-MNDA Polyclonal Lapin est utilisé pour la détection de MNDA dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour MNDA anticorps (AA 350-430) (ABIN7222516)

Antigène: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MNDA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MNDA anticorps

Épitope: AA 350-430

Fonction: Rabbit Anti-MNDA Polyclonal Antibody

Specificité: MNDA Polyclonal Antibody detects endogenous levels of MNDA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human MNDA at AA range: 350-430

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MNDA

Antigène: MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))

Autre désignation: MNDA

Sujet: MNDA, Myeloid cell nuclear differentiation antigenThe myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

Poids moléculaire: 46kD

ID gène: 4332

UniProt: P41218