NACA anticorps (pSer43)

N° du produit ABIN7222642

Cet anticorps anti-NACA est un anticorps Lapin Polyclonal détectant NACA dans ELISA et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NACA anticorps (pSer43) (ABIN7222642)

Antigène: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NACA est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NACA anticorps

Épitope: pSer43

Fonction: NACA (phospho Ser43) Polyclonal Antibody

Specificité: Phospho-NACA (S43) Polyclonal Antibody detects endogenous levels of NACA protein only when phosphorylated at S43.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human NACA Phospho-Ser43

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur NACA

Antigène: NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

Autre désignation: NACA

Sujet: Rabbit Anti-NACA (phospho Ser43) Polyclonal Antibody,NACA, HSD48, Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC, allergen Hom s 2,NACA encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of NACA on different chromosomes.,Nascent polypeptide-associated complex subunit alpha

ID gène: 4666

UniProt: Q13765

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development