NDE1 anticorps (AA 270-350)

N° du produit ABIN7229926

Cet anticorps anti-NDE1 Polyclonal Lapin (ABIN7229926) détecte spécifiquement NDE1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NDE1 anticorps (AA 270-350) (ABIN7229926)

Antigène: NDE1

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDE1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NDE1 anticorps

Épitope: AA 270-350

Fonction: Rabbit Anti-NDE1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of NDE1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human NDE1 protein at AA range: 270-350

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NDE1

Antigène: NDE1

Autre désignation: NDE1

Sujet: Nuclear distribution protein nudE homolog 1, NudENDE1 (NudE Neurodevelopment Protein 1) encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic.

Poids moléculaire: 38kD

ID gène: 54820

UniProt: Q9NXR1