NKX2-8 anticorps (AA 10-90)

N° du produit ABIN7220988

Cet anticorps Lapin Polyclonal détecte spécifiquement NKX2-8 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NKX2-8 anticorps (AA 10-90) (ABIN7220988)

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NKX2-8 anticorps

Épitope: AA 10-90

Fonction: Rabbit Anti-Nkx-2.8 Polyclonal Antibody

Specificité: Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human Nkx-2.8 at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: Nkx-2.8

Sujet: The NK2 homeobox 8 encoded by NKX2-8 is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Poids moléculaire: 26kD

ID gène: 26257

UniProt: Q8IUT7