NRARP anticorps

N° du produit ABIN7230124

L’anticorps Lapin Polyclonal anti-NRARP a été validé pour WB et ELISA. Il convient pour détecter NRARP dans des échantillons de Humain et Souris.

Aperçu rapide pour NRARP anticorps (ABIN7230124)

Antigène: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRARP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NRARP anticorps

Fonction: NRARP Polyclonal Antibody

Specificité: The antibody detects endogenous levels of NRARP protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human NRARP protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur NRARP

Antigène: NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

Autre désignation: NRARP

Sujet: Rabbit Anti-NRARP Polyclonal Antibody,Notch-regulated ankyrin repeat-containing protein,NRARP (NOTCH Regulated Ankyrin Repeat Protein) is a Protein Coding gene. Among its related pathways are Notch signaling pathway (KEGG). Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal. Involved in angiogenesis acting downstream of Notch at branch points to regulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis. During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior-posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellular domain (NICD) and downregulate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain (By similarity).,NRARP

Poids moléculaire: observerd band 12kDa

ID gène: 441478

UniProt: Q7Z6K4