NUMA1 anticorps (AA 310-390)
Aperçu rapide pour NUMA1 anticorps (AA 310-390) (ABIN7222852)
Antigène
Voir toutes NUMA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 310-390
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Fonction
- NuMA Polyclonal Antibody
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Specificité
- NuMA Polyclonal Antibody detects endogenous levels of NuMA protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the N-terminal region of human NuMA at AA range: 310-390
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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Autre désignation
- NuMA
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Sujet
- Rabbit Anti-NuMA Polyclonal Antibody,NUMA1, NUMA, Nuclear mitotic apparatus protein 1, NuMA protein, SP-H antigen,NUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.,Nuclear mitotic apparatus protein 1
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Poids moléculaire
- observerd band 240kDa
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ID gène
- 4926
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UniProt
- Q14980
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
Antigène
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