NFX1 anticorps (AA 80-160)

N° du produit ABIN7229984

Cet anticorps Lapin Polyclonal détecte spécifiquement NFX1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour NFX1 anticorps (AA 80-160) (ABIN7229984)

Antigène: NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFX1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NFX1 anticorps

Épitope: AA 80-160

Fonction: Rabbit Anti-NFX1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of NFX1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human NFX1 protein at AA range: 80-160

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NFX1

Antigène: NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))

Autre désignation: NFX1

Sujet: Transcriptional repressor NF-X1, Nuclear transcription factor, X box-binding protein 1MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by NFX1 (Nuclear Transcription Factor, X-Box Binding 1) is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

Poids moléculaire: 123kD

ID gène: 4799

UniProt: Q12986