NME2 anticorps (AA 80-160)

N° du produit ABIN7216358

L’anticorps anti-NME2 Polyclonal Lapin est utilisé pour la détection de NME2 dans des échantillons de Humain, Souris et Singe. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour NME2 anticorps (AA 80-160) (ABIN7216358)

Antigène: NME2 (Nucleoside diphosphate kinase B (NME2))

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NME2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-NME2 anticorps

Épitope: AA 80-160

Fonction: Rabbit Anti-p18 Polyclonal Antibody

Specificité: P18 Polyclonal Antibody detects endogenous levels of p18 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human p18 at AA range: 80-160

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NME2

Antigène: NME2 (Nucleoside diphosphate kinase B (NME2))

Autre désignation: p18

Sujet: CDKN2C, CDKN6, Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6Cyclin dependent kinase inhibitor 2C encoded by CDKN2C is a member of the INK4 family of cyclin-dependent kinase inhibitors. Cyclin dependent kinase inhibitor 2C has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of CDKN2C was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of CDKN2C in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of CDKN2C, which encode an identical protein, have been reported.

Poids moléculaire: 18kD

ID gène: 1031

UniProt: P42773