Oncostatin M anticorps (AA 50-100)

N° du produit ABIN7230418

L’anticorps Lapin Polyclonal anti-Oncostatin M a été validé pour ELISA et IHC (p). Il convient pour détecter Oncostatin M dans des échantillons de Humain.

Aperçu rapide pour Oncostatin M anticorps (AA 50-100) (ABIN7230418)

Antigène: Oncostatin M (OSM)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Oncostatin M est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Oncostatin M anticorps

Épitope: AA 50-100

Fonction: OSM Polyclonal Antibody

Specificité: The antibody detects endogenous levels of OSM

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human OSM protein at AA range: 50-100

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Oncostatin M

Antigène: Oncostatin M (OSM)

Autre désignation: OSM

Sujet: Rabbit Anti-OSM Polyclonal Antibody,Oncostatin-M, OSM,OSM encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. OSM and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,OSM

ID gène: 5008

UniProt: P13725

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion