Oncostatin M anticorps (AA 50-100)

N° du produit ABIN7230418

L’anticorps anti-Oncostatin M Polyclonal Lapin est utilisé pour la détection de Oncostatin M dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, IHC et IF.

Aperçu rapide pour Oncostatin M anticorps (AA 50-100) (ABIN7230418)

Antigène: Oncostatin M (OSM)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Oncostatin M est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Oncostatin M anticorps

Épitope: AA 50-100

Fonction: Rabbit Anti-OSM Polyclonal Antibody

Specificité: The antibody detects endogenous levels of OSM

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human OSM protein at AA range: 50-100

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Oncostatin M

Antigène: Oncostatin M (OSM)

Autre désignation: OSM

Sujet: Oncostatin-M, OSMOSM encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. OSM and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

ID gène: 5008

UniProt: P13725

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion