OPRK1 anticorps (AA 290-370)

N° du produit ABIN7222868

L’anticorps anti-OPRK1 Polyclonal Lapin est utilisé pour la détection de OPRK1 dans des échantillons de Humain, Rat, Souris et Singe. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour OPRK1 anticorps (AA 290-370) (ABIN7222868)

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPRK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-OPRK1 anticorps

Épitope: AA 290-370

Fonction: Rabbit Anti-KOR-1 Polyclonal Antibody

Specificité: KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human KOR-1 at AA range: 290-370

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur OPRK1

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Autre désignation: KOR-1

Sujet: OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in OPRK1 have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Poids moléculaire: 48kD

ID gène: 4986

UniProt: P41145