OPN4 anticorps (AA 400-480)

N° du produit ABIN7215736

Cet anticorps anti-OPN4 est un anticorps Lapin Polyclonal détectant OPN4 dans WB, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour OPN4 anticorps (AA 400-480) (ABIN7215736)

Antigène: OPN4 (Opsin 4 (OPN4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPN4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-OPN4 anticorps

Épitope: AA 400-480

Fonction: Melanopsin Polyclonal Antibody

Specificité: Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Melanopsin at AA range: 400-480

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur OPN4

Antigène: OPN4 (Opsin 4 (OPN4))

Autre désignation: Melanopsin

Sujet: Rabbit Anti-Melanopsin Polyclonal Antibody,OPN4, MOP, Melanopsin, Opsin-4,Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. Melanopsin functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,Melanopsin

Poids moléculaire: observerd band 55kDa

ID gène: 94233

UniProt: Q9UHM6