Pan Myristoylation anticorps

N° du produit ABIN7226980

L’anticorps anti-Pan Myristoylation Polyclonal Lapin est utilisé pour la détection de Pan Myristoylation dans des échantillons de Différentes espèces. Il a été validé pour ELISA et WB.

Aperçu rapide pour Pan Myristoylation anticorps (ABIN7226980)

Antigène: Pan Myristoylation

Reactivité: Différentes espèces

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Détail du produit

Fonction: Rabbit Anti-Pan myristoylation Polyclonal Antibody

Specificité: The antibody detects endogenous myristoylated protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic myristoylated peptide

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: Pan Myristoylation

Sujet: Pan3 (PAB-dependent poly(A)-specific ribonuclease subunit 3) is a 741 amino acid cytoplasmic protein belonging to the protein kinase superfamily. Containing a protein kinase domain, Pan3 is a component of the Pan nuclease complex and recruits polyadenylate-binding protein, which in turn stimulates Pan2 nuclease activity. It is suggested that Pan3 may have a functional role in cytoplasmic mRNA decay. Pan3 exists as three isoforms produced by alternative splicing and the gene encoding Pan3 is located on human chromosome 13. Chromosome 13 houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Poids moléculaire: 130kD,80kD,35kD