PFKL anticorps (AA 660-740)

N° du produit ABIN7216516

Cet anticorps Lapin Polyclonal détecte spécifiquement PFKL dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PFKL anticorps (AA 660-740) (ABIN7216516)

Antigène: PFKL (Phosphofructokinase, Liver (PFKL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PFKL anticorps

Épitope: AA 660-740

Fonction: Rabbit Anti-PFK-B Polyclonal Antibody

Specificité: PFK-B Polyclonal Antibody detects endogenous levels of PFK-B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human PFK-B at AA range: 660-740

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PFKL

Antigène: PFKL (Phosphofructokinase, Liver (PFKL))

Autre désignation: PFK-B

Sujet: PFKL, 6-phosphofructokinase, liver type, Phosphofructo-1-kinase isozyme B, PFK-B, Phosphofructokinase 1, PhosphohexokinasePFKL encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 85kD

ID gène: 5211

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, L'effet Warburg