PFKM anticorps (Internal Region)

N° du produit ABIN7216508

L’anticorps Lapin Polyclonal anti-PFKM a été validé pour WB, ELISA et IHC (p). Il convient pour détecter PFKM dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PFKM anticorps (Internal Region) (ABIN7216508)

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PFKM anticorps

Épitope: Internal Region

Fonction: PFKM Polyclonal Antibody

Specificité: PFKM Polyclonal Antibody detects endogenous levels of PFKM protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human PFKM

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PFKM

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFKM

Sujet: Rabbit Anti-PFKM Polyclonal Antibody,PFKM, PFKX, 6-phosphofructokinase, muscle type, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphofructokinase-M, Phosphofructokinase 1, Phosphohexokinase,Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. PFKM encodes the muscle-type isozyme. Mutations in PFKM have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.,6-phosphofructokinase muscle type

Poids moléculaire: observerd band 85kDa

ID gène: 5213

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg