Plakophilin 2 anticorps (AA 610-690)

N° du produit ABIN7216602

Cet anticorps anti-Plakophilin 2 Polyclonal Lapin (ABIN7216602) détecte spécifiquement Plakophilin 2 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour Plakophilin 2 anticorps (AA 610-690) (ABIN7216602)

Antigène: Plakophilin 2 (PKP2)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Plakophilin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Plakophilin 2 anticorps

Épitope: AA 610-690

Fonction: Rabbit Anti-Plakophilin 2 Polyclonal Antibody

Specificité: Plakophilin 2 Polyclonal Antibody detects endogenous levels of Plakophilin 2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Plakophilin 2 at AA range: 610-690

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Plakophilin 2

Antigène: Plakophilin 2 (PKP2)

Autre désignation: Plakophilin 2

Sujet: PKP2, Plakophilin-2PKP2 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

Poids moléculaire: 97kD

ID gène: 5318

UniProt: Q99959

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2