Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2) (AA 170-250) anticorps

N° du produit ABIN7230470

Cet anticorps anti-Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 Polyclonal Lapin (ABIN7230470) détecte spécifiquement Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2) (AA 170-250) anticorps (ABIN7230470)

Antigène: Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Détail du produit

Épitope: AA 170-250

Fonction: Rabbit Anti-PABP2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PABP2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PABP2 protein at AA range: 170-250

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: Poly(A) Binding Protein, Cytoplasmic, Pseudogene 2 (PABPCP2)

Autre désignation: PABP2

Sujet: Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2, Nuclear poly(A)-binding protein 1, Poly(A)-binding protein II, PABII, Polyadenylate-binding nuclear protein 1PABPN1 (Poly(A) Binding Protein Nuclear 1) encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. PABPN1 contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.

Poids moléculaire: 33kD

ID gène: 8106

UniProt: Q86U42