POLE anticorps (AA 1230-1310)

N° du produit ABIN7223256

Cet anticorps anti-POLE Polyclonal Lapin (ABIN7223256) détecte spécifiquement POLE dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour POLE anticorps (AA 1230-1310) (ABIN7223256)

Antigène: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLE est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-POLE anticorps

Épitope: AA 1230-1310

Fonction: Rabbit Anti-DNA pol ε A Polyclonal Antibody

Specificité: DNA pol ε A Polyclonal Antibody detects endogenous levels of DNA pol ε A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human DNA pol epsilon A at AA range: 1230-1310

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur POLE

Antigène: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Autre désignation: DNA pol epsilon A

Sujet: POLE, POLE1, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit APOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

ID gène: 5426

UniProt: Q07864

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA