Prohibitin 2 anticorps
Aperçu rapide pour Prohibitin 2 anticorps (ABIN7230616)
Antigène
Voir toutes Prohibitin 2 (PHB2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PHB2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of PHB2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human PHB2 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Prohibitin 2 (PHB2)
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Autre désignation
- PHB2
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Sujet
- Rabbit Anti-PHB2 Polyclonal Antibody,B-cell receptor-associated protein BAP37, D-prohibitin, Repressor of estrogen receptor activity,PHB2 (Prohibitin 2) is a Protein Coding gene. Diseases associated with PHB2 include Urethritis and Loiasis. Among its related pathways are GPCR Pathway and MAPK Signaling: mitogen Stimulation Pathway. GO annotations related to this gene include estrogen receptor binding. Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.,PHB2
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Poids moléculaire
- observerd band 32kDa
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ID gène
- 11331
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UniProt
- Q99623
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Antigène
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