Prolactin Receptor anticorps (AA 80-160)
Aperçu rapide pour Prolactin Receptor anticorps (AA 80-160) (ABIN7230782)
Antigène
Voir toutes Prolactin Receptor (PRLR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 80-160
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Fonction
- Rabbit Anti-PRLR Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of PRLR protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human PRLR protein at AA range: 80-160
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Prolactin Receptor (PRLR)
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Autre désignation
- PRLR
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Sujet
- Prolactin receptor, PRL-RPRLR encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for PRLR, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
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Poids moléculaire
- 68kD
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ID gène
- 5618
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UniProt
- P16471
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Pathways
- Signalistation JAK/STAT, Response to Growth Hormone Stimulus
Antigène
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