PRSS2 anticorps (AA 40-120)
Aperçu rapide pour PRSS2 anticorps (AA 40-120) (ABIN7231936)
Antigène
Voir toutes PRSS2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 40-120
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Fonction
- Rabbit Anti-TRY2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of TRY2 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human TRY2 protein at AA range: 40-120
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))
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Autre désignation
- TRY2
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Sujet
- Anionic trypsinogen, Serine protease 2, Trypsin IIPRSS2 belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 27kD
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ID gène
- 5645
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UniProt
- P07478
Antigène
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