PRSS2 anticorps
Aperçu rapide pour PRSS2 anticorps (ABIN7269580)
Antigène
Voir toutes PRSS2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PRSS2 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human PRSS2.
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))
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Autre désignation
- PRSS2
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Sujet
- This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.,PRSS2, TRY2, TRY8, TRYP2, trypsin-2,Cell Biology & Developmental Biology,Ubiquitin,PRSS2
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Poids moléculaire
- 30kDa
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ID gène
- 5645
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UniProt
- P07478
Antigène
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